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| The
Exhibits Hall 2007 |
| Oundle
School, Northants - Thursday 15th March 2007 |
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Back to Main Exhibit Hall Page
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Blood
Pressure, Microcirculation and Cardiovascular Risk
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Clinical
Sciences Research Institute, University of Warwick, University Hospital-UHCW,
COVENTRY CV2 2DX
Prof Donald Singer
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The capillaries
are the smallest blood vessels. They are important for gas exchange
in the lungs, and for providing nutrition and removing waste products
in tissues throughout the body. The lining endothelial cells produce
potent hormonal factors such as the gas nitric oxide, which relaxes
blood vessels, and endothelin, which constricts vessels. The primitive
form of endothelin forms a toxin in scorpions and in the asp, which
is said to have caused the death of Cleopatra by inducing severe
narrowing of the coronary arteries leading to a fatal heart attack.
Reduced capillary
density occurs with cardiovascular risk factors, as well in established
cardiovascular disease, as a result of endothelial cell [EC] degeneration
or a decrease in the ability of endothelial cells to form new blood
vessels. Capillary numbers are reduced in patients with high blood
pressure as well as in their children. It is now possible to see
capillaries in life, using a specialised imaging method called capillary
videomicroscopy. At this exhibit you will be able to: find out more
about high blood pressure, have your blood pressure measured, and
see capillary videomicroscopy in action. take part in a keypad interactive
quiz about heart disease.
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Capillary microscope
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The
Poster
Presentations are judged and prizes totalling
£1500
are to be awarded at Showase Science 2007.
Click
on images to enlarge
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